Prof. Dr. Julia Herzen, TUM

Advanced methods in x-ray Imaging - from x-ray physics to biomedical applications

Since the discovery of X-rays in 1895, the X-ray imaging has been an indispensable technique in diagnostic and industrial imaging. While the machines constantly improved over time, the way the contrast is generated has not changed over one century – only the attenuation of X-rays has been used as a contrast mechanism. Over the last two decades, phase-contrast X-ray imaging has been developed using the refraction of X-rays to generate the contrast. This kind of imaging has been demonstrated to provide superior soft-tissue contrast in comparison to conventional attenuation-based X-ray imaging. However, visualizing biomedical soft tissue at high spatial resolution and high image quality still has been limited to brilliant synchrotron radiation sources with its very limited access. Thus, the possibility to perform high-quality X-ray phase-contrast computed tomography with laboratory setups is of great interest for a broad range of biomedical applications. We designed and built an imaging setup using a standard X-ray source and reaching comparable image quality as synchrotron-based instruments. Here, the performance of our instrument will be reviewed by highlighting the recent results on biomedical soft-tissue analysis of different human diseases.

Katharina Niepel (Project B4)

Animal tissue-based quantitative comparison of dual-energy CT to SPR converson methods using high-Resolution gel dosimetry

Christian Heckl (Project C6)

Spectroscopy for point-of-care diagnostics

Date and Time

12.10.2020

15:00 

Location

ZOOM Meeting

Attending PIs

Prof. Dr. Katia Parodi,  Prof. Dr. Julia Herzen, Prof. Dr. Ronald Sroka