A1 Hybrid patient model for MC computing

The goal of this project is to design, validate, and implement a patient specific whole body phantom to predict out-of-field dose and secondary cancer risk from radiotherapy, with a particular interest in neutron dose produced during proton therapy. A method has been developed to flexibly create a hybrid phantom for male and female patients for any given treatment site. Using the planning patient CT data and a generic adult computational phantom scaled to patient measurements, a whole body patient specific hybrid can be stitched together to allow dose prediction in anatomical regions outside of the treatment field. Particularly in the case of proton therapy, there is unaccounted for out-of-field neutron dose, which can change the patient's risk of developing secondary cancer. This hybrid seeks to provide a method of estimating out-of-field dose and secondary cancer risk to an individual patient prior to treatment and to facilitate including secondary cancer risk as a factor in the treatment planning process.